Lee, Y.S, Molineux I.J, Yin, Y.W, "A single mutation in human mitochondrial DNA polymerase pol gammaA affects both polymerization and proofreading activities, but only as a holoenzyme", J Biol Chem, 2010 May 30. [Epub ahead of print]. pdf

Lee, YS, Lee, SJ, Demeler, D.,Molineux, I.J., Johnson, K.A., Yin, Y.W., "Each monomer of the dimeric accessory protein for human mitochondrial DNA polymerase has a distinct role in conferring processivity", J Biol Chem, 2010 8;285(2):1490-9. pdf

Lee, YS, Kennedy, W.D., Yin, Y.W., "Structural insights into human mitochondrial DNA replication and disease-related polymerase mutations", Cell, 2009, 139(2):312-24pdf.  

Commentary  Cell. 2009 Oct 16;139(2):231-3))

Kennedy, P.W., Momand, R.J., and Yin, Y. W, “Mechanism for de novo RNA synthesis and initiating nucleotide specificity by T7 RNA polymerase. J Mol Biol. 2007  370(2):256-68.  pdf

 Challa, M, Malladi,S, Pellock, B.J, Dresnek, D, Varadarajan, S, Yin, Y. W, White, K, Bratton, S.B,       "Drosophila Omi, a mitochondrial-localized IAP antagonist and proapoptotic serine protease", 2007, EMBO J  26(13):3144-56. pdf

 Yin, Y. W and Steitz, T. A, "Mechanism for T7 RNA polymerase translocation and helicase activity".   2004, Cell, 116(3):393-404. pdf

 Rataileau, P, Huang, X, Yin, Y. W, Vachette, P, Vonrhein .C, Bricogne, G, Roversi, P, Ilyin, V, Carter, C.W Jr, “2.2 Å crystal structure of tryptophanyl-tRNA synthetase complexed with ATP in a closed, pre-transition-state conformation”, 2003, J Mol Biol. 325(1): 39-63. pdf

 Yin, Y. W. and Steitz, T. A:  “Structural basis for the transition from initiation to elongation transcription in T7 RNA polymerase”.  2002, Science, 298(5597):1387-95. pdf

 Carter CW Jr, Ilyin V, Yin Y, Huang X and Retailleau P: The TrpRS Conformations Stabilize a Dynamic, Dissociative Transition State in Using Crystallography to Understand Enzyme Mechanisms.  Transactions of the American Crystallographic Association, Inc 35:19-36, 2001.

Rateileau, P, Yin, Y, Hu M, Roach J, Bricogne G, Vonrhein C, Roversi P, Blanc E, Sweet RM, Carter CW Jr. “High-resolution experimental phases for tryptophanyl-tRNA synthetase (TrpRS) complexed with tryptophanyl-5'AMP”.  2001, Acta Crystallogr D57:1595-608  pdf

  Ilyin, V., Li, G., Temple, B., Yin, Y., Carter, C. W. Jr. “2.9Å crystal structure of ligand-free Tryptophanyl tRNA synthetase Domain Movements Fragment the Adenine Nucleotide Binding Site”, 2000, Protein Science,  9, 218-231. pdf

 Yin, Y. and Carter, C. W. "Incomplete Factorial Design and Response Surfaces Methods: Yield Optimization of tRNATrp from in vitro T7 RNA Polymerase Transcription."  1996, Nucleic Acids Res.  24, 1279-1286. pdf

Carter, C. W. and Yin, Y. "Quantitative Analysis in the Characterization and Optimization of Protein Crystal Growth."  1994, Acta.Cryst.D50, 572-590. pdf

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